Original PDF Ebook – DNA Repair in Cancer Therapy2nd EditionMolecular Targets and Clinical Applications – 9780128035825

Original PDF Ebook – DNA Repair in Cancer Therapy2nd EditionMolecular Targets and Clinical Applications – 9780128035825

DNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition provides a comprehensive and timely reference that focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhancement of cancer treatment._x000D_
Experts on DNA repair proteins from all areas of cancer biology research take readers from bench research to new therapeutic approaches. This book provides a detailed discussion of combination therapies, in other words, how the inhibition of repair pathways can be coupled with chemotherapy, radiation, or DNA damaging drugs._x000D_
Newer areas in this edition include the role of DNA repair in chemotherapy induced peripheral neuropathy, radiation DNA damage, Fanconi anemia cross-link repair, translesion DNA polymerases, BRCA1-BRCA2 pathway for HR and synthetic lethality, and mechanisms of resistance to clinical PARP inhibitors._x000D_
Provides a comprehensive overview of the basic and translational research in DNA repair as a cancer therapeutic target_x000D_
Includes timely updates from the earlier edition, including Fanconi Anemia cross-link repair, translesion DNA polymerases, chemotherapy induced peripheral neuropathy, and many other new areas within DNA repair and cancer therapy_x000D_
Saves academic, medical, and pharma researchers time by allowing them to quickly access the very latest details on DNA repair and cancer therapy_x000D_
Assists researchers and research clinicians in understanding the importance of the breakthroughs that are contributing to advances in disease-specific research